Tilorone
The mechanism of antiviral action is associated with inhibition of translation of virus-specific proteins in infected cells, thus inhibiting the reproduction of viruses. The second mechanism is via the stimulation of the generation of a-b-g-interferon.
Brand names: Amixin IC, Amiksin IC (alternate machine-generated English translation), Lavomax
Usages
According to a manufacturer's website (Interchem):
- Viral hepatitis A, B, C
- Herpes
- Cytomegalovirus infection
- Urogenital and respiratory chlamydia
- Treatment and prevention of influenza and acute respiratory viral infections.
- Neuroviral infections: infectious-allergic and viral encephalomyelitis (multiple sclerosis, panencephalitis, uveoencephalitis and meningoencephalitis).
- To counteract (or compensate for) the degree of immunosuppression in the 'complex therapy' of diseases that are accompanied by secondary induced immunodeficiencies and require immunocorrection
Potential other uses:
- HPV - "The experience of the drug in the treatment of this viral infection exists, but you should consult your doctor on this issue."
- Herpes - "Such experience exists and to determine the possibility of using the drug for the prevention of herpes you need to consult a doctor dermatovenereologist."
- Potential use for SARS-CoV-2 prophylaxis and treatment
Side effects and safety information
- X Not for pregnant mothers and women who may become pregnant
- X Not for children under 7 years
In some cases are possible dyspeptic phenomena, short-term fever; in rare cases - allergic reactions such as skin rash, pruritus, urticaria. Contraindications for use of Amixin® ІC - is increased individual sensitivity to the drug, pregnancy and lactation, age under 7 years.
https://interchem.ua/en/faq#drug_26
- This medicine contains dyes that may cause allergic reactions.
- There is no experience with the use of the drug during pregnancy and breastfeeding, so it is contraindicated in these periods.
- Ability to influence the speed of reaction when driving a car or other machinery: Does not affect.
Adverse reactions
- From the skin and subcutaneous tissue: allergic reactions, including angioneurotic edema, rash (including urticaria), redness of the skin, dry skin, itching.
- From the gastrointestinal tract: bitterness in the mouth, dyspepsia (including epigastric pain, nausea, heartburn), diarrhea.
- Dyspepsia = indigestion; refers to discomfort or pain that occurs in the upper abdomen (epigastric)
- General disorders: general weakness, lethargy, loss of appetite, short-term fever.
Interchem instructions
Instructions: https://interchem.ua/uploads/drugs/am%D1%96ksin_R_IC_%D1%96nstr_sait.pdf
Machine translated version: https://docs.google.com/document/d/1cwvkh0GPbPsL_r1_6sb9Ie2WEMuTxLmu1z2uSyvcJwc/edit?usp=sharing
PDF version of machine translation: https://www.longhaulwiki.com/resources/assets/am%D1%96ksin_translated.pdf
Method of application and dosage
Take orally after a meal.
Adults
- In the treatment of influenza and acute respiratory viral infections: in the first 2 days of treatment - 125 mg, then - 125 mg in 48 hours. Course dose - 750 mg. (Editor's note: the instructions imply that the dose should be repeated every 2 days until the cumulative dose is 750mg)
- For the prevention of influenza and acute respiratory viral infections: 125 mg once a week for 6 weeks.
- Treatment of viral hepatitis A: on the 1st day of treatment - 125 mg 2 times, then - 125 mg after 48 hours. Course dose - 1.25 g.
- Prevention of hepatitis A: 125 mg once a week for 6 weeks.
For a full list of application instructions, see the Interchem instructions.
Storage
Store in the original package at a temperature not exceeding 25 ° C. Keep out of reach of children.
Expiration date. 4 years.