User:User123

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Revision as of 04:10, 9 September 2022 by User123 (talk | contribs) (→‎TLR4)
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Stuff I'm working on

Post_vaccination_syndrome_introduction_for_practitioners

https://docs.google.com/document/d/1UgVw3wa43hzORX4wzCDfLldfiO0D_bRcD1G_HJFq0bQ/edit?usp=sharing - A theory regarding the cause of vaccine injury

Other_treatments

Super antigen theory notes

https://sci-hub.se/https://doi.org/10.1016/0882-4010(87)90003-9 - In the TMEV virus, inbred mice can be susceptible or resistant to the virus.

https://www.nature.com/articles/s41422-021-00495-9 - SARS COV 2 spike protein activates TLR4 and acts as a superantigen

TLR4

https://pubmed.ncbi.nlm.nih.gov/18203139/ - !!! The TLR4 pathway seems to regulate the priming of Th17 cells and reduce the severity of EAE.

https://pubmed.ncbi.nlm.nih.gov/19211042/ - "TLR4 down regulates disease severity in EAE and Th17 cell responses"

https://pubmed.ncbi.nlm.nih.gov/21685327/ - This study had conflicting results. TLR4 knockout mice had the same susceptibility to disease.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1375233/ - TLR4 ligands include LPS, Taxol

https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0625-x - LPS is used to treat cancer as a TLR4 ligand / vaccine adjuvant.

https://pubmed.ncbi.nlm.nih.gov/12799214/ - LPS is used in Experimental autoimmune thyroiditis (EAT) model. LPS and Freund's adjuvant behave differently.

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