Tilorone

The mechanism of antiviral action is associated with inhibition of translation of virus-specific proteins in infected cells, thus inhibiting the reproduction of viruses. The second mechanism is via the stimulation of the generation of a-b-g-interferon.

Brand names: Amixin IC, Amiksin IC (alternate machine-generated English translation), Lavomax

Usages

According to a manufacturer's website (Interchem):

• Viral hepatitis A, B, C
• Herpes
• Cytomegalovirus infection
• Urogenital and respiratory chlamydia
• Treatment and prevention of influenza and acute respiratory viral infections.
• Neuroviral infections: infectious-allergic and viral encephalomyelitis (multiple sclerosis, panencephalitis, uveoencephalitis and meningoencephalitis).
• To counteract (or compensate for) the degree of immunosuppression in the 'complex therapy' of diseases that are accompanied by secondary induced immunodeficiencies and require immunocorrection

Potential other uses:

• HPV - "The experience of the drug in the treatment of this viral infection exists, but you should consult your doctor on this issue."
• Herpes - "Such experience exists and to determine the possibility of using the drug for the prevention of herpes you need to consult a doctor dermatovenereologist."
• Potential use for SARS-CoV-2 prophylaxis and treatment

Side effects and safety information

• X Not for pregnant mothers and women who may become pregnant
• X Not for children under 7 years

In some cases are possible dyspeptic phenomena, short-term fever; in rare cases - allergic reactions such as skin rash, pruritus, urticaria. Contraindications for use of Amixin® ІC - is increased individual sensitivity to the drug, pregnancy and lactation, age under 7 years.

https://interchem.ua/en/faq#drug_26

• This medicine contains dyes that may cause allergic reactions.
• There is no experience with the use of the drug during pregnancy and breastfeeding, so it is contraindicated in these periods.
• Ability to influence the speed of reaction when driving a car or other machinery: Does not affect.

Source: https://interchem.ua/uploads/drugs/am%D1%96ksin_R_IC_%D1%96nstr_sait.pdf Machine translated version: https://docs.google.com/document/d/1cwvkh0GPbPsL_r1_6sb9Ie2WEMuTxLmu1z2uSyvcJwc/edit?usp=sharing

Method of application and dosage

Take orally after a meal.

Adults

• In the treatment of influenza and acute respiratory viral infections: in the first 2 days of treatment - 125 mg, then - 125 mg in 48 hours. Course dose - 750 mg. (Editor's note: the instructions imply that the dose should be repeated every 2 days until the cumulative dose is 750mg)
• For the prevention of influenza and acute respiratory viral infections: 125 mg once a week for 6 weeks.
• Treatment of viral hepatitis A: on the 1st day of treatment - 125 mg 2 times, then - 125 mg after 48 hours. Course dose - 1.25 g.
• Prevention of hepatitis A: 125 mg once a week for 6 weeks.