User:User123: Difference between revisions

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Tag: Manual revert
 
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[[Other_treatments]]
[[Other_treatments]]


== Super antigen theory notes ==
== Superantigen theory notes ==


https://sci-hub.se/https://doi.org/10.1016/0882-4010(87)90003-9 - In the TMEV virus, inbred mice can be susceptible or resistant to the virus.
[[Spike_as_a_superantigen|SARS-CoV-2 spike as a superantigen]]
 
https://www.nature.com/articles/s41422-021-00495-9 - SARS COV 2 spike protein activates TLR4 and acts as a superantigen
 
=== TLR4 ===
https://pubmed.ncbi.nlm.nih.gov/18203139/ - !!! The TLR4 pathway seems to regulate the priming of Th17 cells and reduce the severity of EAE.
 
https://pubmed.ncbi.nlm.nih.gov/19211042/ - "TLR4 down regulates disease severity in EAE and Th17 cell responses"
 
https://pubmed.ncbi.nlm.nih.gov/21685327/ - This study had conflicting results.  TLR4 knockout mice had the same susceptibility to disease.
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1375233/ - TLR4 ligands include LPS, Taxol
 
https://jitc.biomedcentral.com/articles/10.1186/s40425-019-0625-x - LPS is used to treat cancer as a TLR4 ligand / vaccine adjuvant.
 
https://pubmed.ncbi.nlm.nih.gov/12799214/ - LPS is used in  Experimental autoimmune thyroiditis (EAT) model.  LPS and Freund's adjuvant behave differently.
 
http://www.worldcat.org/title/1051926526 - LPS and Freund's are used in the livestock industry to $$$
 
=== Myocarditis ===
 
https://onlinelibrary.wiley.com/doi/full/10.1002/iid3.155 - Autoimmune myocarditis model, CFA / TiterMax Gold Adjuvant + myocarditogenic peptides in male mice
 
https://pubmed.ncbi.nlm.nih.gov/31005592/ - Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway

Latest revision as of 03:52, 10 April 2023

Stuff I'm working on[edit]

Post_vaccination_syndrome_introduction_for_practitioners

https://docs.google.com/document/d/1UgVw3wa43hzORX4wzCDfLldfiO0D_bRcD1G_HJFq0bQ/edit?usp=sharing - A theory regarding the cause of vaccine injury

Other_treatments

Superantigen theory notes[edit]

SARS-CoV-2 spike as a superantigen

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