Delayed onset of vaccine injury: Difference between revisions
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Some evidence suggests that COVID vaccines can lead to delayed and serious reactions weeks after initial vaccination. | Some evidence suggests that COVID vaccines can lead to delayed and serious reactions weeks after initial vaccination. Some case reports indicate onset 10 weeks after vaccination. | ||
== MIS-V == | == MIS-V == | ||
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Symptoms of MIS-C/A/V are similar to Kawasaki disease. | Symptoms of MIS-C/A/V are similar to Kawasaki disease. | ||
=== Published case reports on MIS-V === | |||
* [https://casereports.bmj.com/content/14/7/e243888 Nune et al.] - 2 days to onset, 44 year old female. "we highlight the first reported MIS-V case after the SARS-CoV-2 vaccine" | |||
* [https://doi.org/10.3201/eid2802.211938 Choi et al.] - 10 days to onset, 22 year old female. "Ten days after receiving the first dose of coronavirus disease vaccine, a 22-year-old woman in South Korea experienced myocarditis, myopathy, pericarditis, and gastroenteritis; rash subsequently developed." | |||
* '''[https://doi.org/10.3201/eid2711.211612 Grome et al.] - 22 days to onset''', male healthcare worker in his 30s. "a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination." | |||
* [https://doi.org/10.3201%2Feid2707.210594 Salzman et al.] - Onset not clear, 20 year old female, vaccinated 15 days before hospital admission. | |||
* '''[https://doi.org/10.3390/vaccines9111353 Buchhorn et al.] - Onset 10 weeks after vaccination''', 18 year old male. | |||
===Selected VAERS case reports=== | ===Selected VAERS case reports=== | ||
Revision as of 14:49, 7 August 2022
Some evidence suggests that COVID vaccines can lead to delayed and serious reactions weeks after initial vaccination. Some case reports indicate onset 10 weeks after vaccination.
MIS-V
Multisystem Inflammatory Syndrome (MIS) is labelled as MIS-C when it develops in children following a COVID-19 infection. In rare cases, it can develop in adults (MIS-A). Various published case reports have noted that it can also develop after vaccination (MIS-V) without any evidence of a prior COVID-19 infection. Onset of MIS-V can be weeks after initial infection.
Symptoms of MIS-C/A/V are similar to Kawasaki disease.
Published case reports on MIS-V
- Nune et al. - 2 days to onset, 44 year old female. "we highlight the first reported MIS-V case after the SARS-CoV-2 vaccine"
- Choi et al. - 10 days to onset, 22 year old female. "Ten days after receiving the first dose of coronavirus disease vaccine, a 22-year-old woman in South Korea experienced myocarditis, myopathy, pericarditis, and gastroenteritis; rash subsequently developed."
- Grome et al. - 22 days to onset, male healthcare worker in his 30s. "a fatal case of multisystem inflammatory syndrome in an adult with onset 22 days after a second dose of mRNA coronavirus disease vaccine. Serologic and clinical findings indicated severe acute respiratory syndrome coronavirus 2 infection occurred before vaccination."
- Salzman et al. - Onset not clear, 20 year old female, vaccinated 15 days before hospital admission.
- Buchhorn et al. - Onset 10 weeks after vaccination, 18 year old male.
Selected VAERS case reports
- 2006451 - 12 days to onset, 6 year old female diagnosed with Kawasaki disease.
- 1998916 - 27 days to onset, 9 year old female diagnosed with Kawasaki disease. "5 days after covid-19 pfizer vaccine was given she developed a fever with a mild rash on her extremities. [...] Rash progressed to what appeared to be erythema multiforme, she had conjunctivitis as well as persistent fevers. Ended up being sent to ED on 12/31/21 for leukocytosis and thrombocytopenia [...]"
- 2006451 - 12 days to onset, 6 year old female who was diagnosed with Kawasaki disease. Vaccinated on 12-11-2021, developed rash 12/23.
- 2175151 - 2 days to onset, 15 year old male diagnosed with Kawasaki's disease.
- 2194347 - 69 days to onset, 5 year old female diagnosed with MIS-C. History of Kawasaki disease X2, 2018/2020.
- 2226084 - Kawasaki disease following COVID, vaccination was 266 days ago.
- 2271220 - 54 days to onset, 10 year old male with "MIS-C vs Kawasaki".
- 2271233 - 39 days to onset, 10 year old male. "Constellation of symptoms is concerning for Kawasaki versus MIS-C."
- 2137230 - 43 days to onset, 7 year old male being treated for MIS-C.